Publications from the Copenhagen Puberty Studies I and II
The Copenhagen Puberty Study II (2005-2006)
(list last updated August 2020)
1. Albrethsen J, Johannsen TH, Jørgensen N, Frederiksen H, Sennels HP, Jørgensen HL, Fahrenkrug J, Petersen JH, Linneberg A, Nordkap L, Bang AK, Andersson A-M, Juul A. Evaluation of Serum Insulin-like Factor 3 Quantification by LC-MS/MS as a Biomarker of Leydig Cell Function. J Clin Endocrinol Metab 2020; 105(6)
2. Frederiksen H, Johannsen TH, Andersen SE, Albrethsen J, Landersoe SK, Petersen JH, Andersen AN, Vestergaard ET, Schorring ME, Linneberg A, Main KM, Andersson A-M, Juul A. Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS. J Clin Endocrinol Metab 2020; 105(3):1-15 2019
3. Busch AS, Hollis B, Day FR, Sørensen K, Aksglaede L, Perry JRB, Ong KK, Juul A, Hagen CP. Voice break in boys-temporal relations with other pubertal milestones and likely causal effects of BMI. Hum Reprod 2019; 34(8):1514-1522
2. Frederiksen H, Johannsen TH, Andersen SE, Albrethsen J, Landersoe SK, Petersen JH, Andersen AN, Vestergaard ET, Schorring ME, Linneberg A, Main KM, Andersson A-M, Juul A. Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS. J Clin Endocrinol Metab 2020; 105(3):1-15 2019
3. Busch AS, Hollis B, Day FR, Sørensen K, Aksglaede L, Perry JRB, Ong KK, Juul A, Hagen CP. Voice break in boys-temporal relations with other pubertal milestones and likely causal effects of BMI. Hum Reprod 2019; 34(8):1514-1522
4. Albrethsen J, Frederiksen H, Andersson A-M, Anand-Ivell R, Nordkap L, Bang AK, Jørgensen N, Juul A. Development and validation of a mass spectrometry-based assay for quantification of insulin-like factor 3 in human serum. Clin Chem Lab Med 2018; 56(11):1913-20
5. Busch AS, Hagen CP, Assens M, Main KM, Almstrup K, Juul A. Differential Impact of Genetic Loci on Age at Thelarche and Menarche in Healthy Girls. J Clin Endocrinol Metab 2018; 103(1):228-234 6. Carlsson A, Sørensen K, Andersson A-M, Frederiksen H, Juul A. Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children. Endocr Connect 2018; 7(1):232-238
7. Greiber IK, Hagen CP, Busch AS, Mieritz MG, Aksglæde L, Main K, Almstrup K, Juul A. The AMH genotype (rs10407022 T>G) is associated with circulating AMH levels in boys, but not in girls. Endocr Connect 2018; 7(2):347-354
8. Mouritsen AK, Busch AS, Aksglaede L, Rajpert-De Meyts E, Juul A. Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys. Endocr Connect 2018; 7(3):460-465
9. Ridefelt P, Hilsted L, Juul A, Hellberg D, Rustad P. Pediatric reference intervals for general clinical chemistry components – merging of studies from Denmark and Sweden. Scand J Clin Lab Invest 2018; 78(5):365-372
10. Frederiksen H, Nielsen O, Skakkebaek NE, Juul A, Andersson A-M. UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents. Int J Hyg Environ Health 2017; 220(2):244-53
11. Johansen ML, Hagen CP, Mieritz MG, Wolthers OD, Heuck C, Petersen JH, Juul A. Pubertal Progression and Reproductive Hormones in Healthy Girls with Transient Thelarche. J Clin Endocrinol Metab 2017; 102(3):1001-1008
12. Søeborg T, Frederiksen H, Johannsen TH, Andersson A-M, Juul A. Isotope-dilution TurboFlow-LCMS/MS method for simultaneous quantification of ten steroid metabolites in serum. Clin Chim Acta 2017; 468:180-186
13. Busch AS, Hagen CP, Assens M, Main KM, Almstrup K, Juul A. Differential impact of genetic loci on age at thelarche and menarche in healthy girls. J Clin Endocrinol Metab 2018, 103(1):228-234
16. Lindhardt Johansen M, Hagen CP, Mieritz MG, Wolthers OD, Heuck C, Petersen JH, Juul A. Pubertal Progression and Reproductive Hormones in Healthy Girls with Transient Thelarche. J Clin Endocrinol Metab 2016, 102(3):1001-1008.
17. Frederiksen H, Nielsen O, Skakkebaek NE, Juul A, Andersson AM. UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents. Int J Hyg Envir Health 2016, 220(2Pt A):244-253.
18. Almstrup K, Lindhardt Johansen M, Busch AS, Hagen CP, Nielsen JE, Petersen JH, Juul A. Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood. Sci Rep 2016, 6:28657.
19. Busch AS, Hagen CP, Almstrup K, Juul A. Circulating MKRN3 levels decline during puberty in healthy boys. J Clin Endocrinol Metab 2016, 101(6):2588-93.
20. Busch AS, Hagen CP, Almstrup K, Main KM, Juul A. Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls. Hum Reprod 2016, 31(4):897-904.
21. Mouritsen A, Søeborg T, Hagen CP, Mieritz MG, Johannsen TH, Frederiksen H, Andersson AM, Juul A. Longitudinal changes in serum concentrations of adrenal androgen metabolites and their ratios by LC-MS/MS in healthy boys and girls. Clin Chim Acta. 2015, 450:370-5.
22. Mieritz MG, Rakêt LL, Hagen CP, Nielsen JE, Talman L-LM, Petersen JH, Sommer SH, Main KM, Jørgensen N, Juul A. A Longitudinal Study of Growth, Sex Steroids and Insulin-like Growth Factor I in boys with Physiological Gynaecomastia. J Clin Endocrinol Metab 2015, 100 (10): 3752-9.
23. Känsäkoski J, Raivio T, Juul A, Tommiska J. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty. Pediatr Res 2015, 78 (6): 709-11.
24. Sørensen K, Juul A. Body Mass Index Percentile-for-Age Overestimates Adiposity in Early Compared with Late Maturing Pubertal Children. Eur J Endocrinol 2015, 173 (2): 227-35.
25. Hagen CP, S Rensen K, Mieritz MG, Johannsen TH, Almstrup K, Juul A. Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls. J Clin Endocrinol Metab 2015, 100(5): 1920-6.
26. Lawaetz J, Hagen CP, Mieritz MG, Jensen MB, Petersen JH, Juul A. Evaluation of 451 Danish boys with delayed puberty: Diagnostic use of a new puberty nomogram and effects of oral testosterone therapy. J Clin Endocrinol Metab 2015, 100(4): 1376-85
27. Hagen CP, Mieritz MG, Nielsen JE, Anand-Ivell R, Ivell R, Juul A. Longitudinal assessment of circulating INSL3 levels in healthy peripubertal girls. Fertil Steril 2015, 103(3):780-786.
28. Hagen CP, Sørensen K, Aksglæde L, Mouritsen A, Mieritz MG, Tinggaard J, Wohlfart-Veje C, Petersen JH, Main KM , Rajpert-DeMeyts E, Almstrup K, Juul A. Pubertal Onset in healthy girls is strongly influenced by genetic variation affecting FSH action. Scientific Reports 2014, 4:6412.
29. Søeborg T, Frederiksen H, Mouritsen A, Johannsen TH, Main KM, Jørgensen N, Petersen JH, Andersson AM, Juul A. The Influence of Age, Gender, Pubertal Stage, and Oral Contraceptives on Serum Levels of DHEA, DHEAS, 17α-Hydroxyprogesterone, Δ4-Androstenedione, Testosterone, and their Ratios Determined by TurboFlow-LC-MS/MS in 1798 Healthy Children, Adolescents, and Young Adults. Clinica Chimica Acta 2014, 437:6-13.
30. Bisgaard A, Sorensen K, Johannesen TH, Helge JW, Andersson AM, Juul A. Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and
adolescents. Int J Pediatr Endocrinol 2014, 1:7.
31. Mieritz MG, Sorensen K, Aksglaede L, Mouritsen A, Hagen CP, Hilsted L, Andersson AM,Juul A. Elevated serum levels of Free Triiodothyronine in Adolescent Boys with Gynaecomastia Compared to Controls. Eur J Endocrinol 2014, 171(2):193-8.
32. Mouritsen A, Søeborg T, Holm Johannsen T, Aksglaede L, Sørensen K, Hagen CP, Mieritz MG, Frederiksen H, Andersson AM, Juul A. Longitudinal changes in circulating testosterone levels
determined by LC-MS/MS and by a commercially available radioimmunoassay in healthy girls and boys during the pubertal transition. Horm Res Paediatr 2014, 82(1):12-7.
33. Lindhardt Johansen M, Anand-Ivell R, Mouritsen A, Hagen CP, Mieritz MG, Søeborg T, Johannsen TH, Main KM, Andersson AM, Ivell R, Juul A. Serum levels of Insulin-like factor 3, Anti-Müllerian Hormone, Inhibin B and Testosterone during pubertal transition in healthy boys: A longitudinal pilot study. Reproduction 2014, 147(4):529-35.
34. Tinggaard J, Aksglæde L, Sørensen K, Mouritsen A, Wohlfahrt Veje C, Hagen C, Mieritz MG, Jørgensen N, Wolthers OD, Heuck C, Petersen JH, Main KM, Juul A. The 2014 Danish references from birth to 20 years for height, weight and body mass index. Acta Paed Scand 2014, 103(2):214-24.
35. Mieritz MG, Sørensen K, Aksglæde L, Mouritsen A, Hagen CP, Hilsted L, Andersson AM, Juul A. Elevated serum IGF-I, but unaltered sex steroid levels, in healthy boys with pubertal gynaecomastia. Clin Endocrinol 2013, 80(5):691-8.
36. Munch-Andersen T, Sorensen K, Aachmann-Andersen NJ, Aksglaede L, Juul A, Helge JW. Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. Int
J Circumpolar Health 2013, 7;72.
37. Mouritsen AM, Frederisken H, Sørensen K, Aksglæde L, Hagen C, Skakkebæk NE, Main KM, Andersson AM, Juul A. Urinary Phthalates from 168 Girls and Boys measured twice a year during a 5 Year Period: Associations with Adrenal Androgen Levels and Puberty. J Clin Endocrinol Metab 2013, 98(9): 3755-64.
38. Hagen CP, Aksglaede L, Sørensen K; Mouritsen A,; Mieritz MG, Main KM, Petersen JH, Almstrup K, Rajpert-De Meyts E, Anderson RA, Juul A. FSHB –211 and FSHR 2039 polymorphisms affect serum levels of FSH and AMH in healthy girls: a longitudinal cohort study. Fertil Steril 2013, 100(4):1089-95.
39. Nielsen J, Jensen RB, Juul A. Increased Sex Hormone-Binding Globulin Levels in Children and Adolescents with thyrotoxicosis. Horm Res Pediatr 2013, 79: 157-61.
40. Søeborg T, Frederiksen H, Fruekilde P, Johannsen TH, Juul A, Andersson AM. Serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, ∆4-androstenedione and testosterone in children determined by TurboFlow-LC-MS/MS Clinica Chimica Acta 2013, 419: 95-101.
41. Frederiksen H, Aksglæde L, Sørensen K, Nielsen O, Main KM, Skakkebæk NE, Juul A, Andersson AM. Bisphenol A and other phenols in urine from Danish children and adolescents analyzed by isotope diluted TurboFlow-LC-MS/MS. Int J Hygiene Envir Health 2013, S1438-4639(13)00016-3.
42. Mouritsen A, Hagen CP, Sørensen K, Aksglæde L, Mieritz MG, Main KM, Almstrup K, Rajpert-DeMeyts E, Juul A. Androgen Receptor CAG Repeat length is Associated with Body Fat and Serum SHBG in Boys: A prospective Cohort Study. J Clin Endocrinol Metab 2013, 98(9): 3755-64.
43. Munch-Andersen T, Sorensen K, Andersen LB, Aachmann-Andersen NJ, Aksglaede L, Juul A, Helge JW. Adverse metabolic risk profiles in Greenlandic Inuit children compared to Danish Children. Obesity 2013, 21(6): 1226-31.
44. Mouritsen A, Aksglæde L, Sørensen K, Hagen CP, Petersen JH, Main KM, Juul A. The Pubertal Transition in 179 Healthy Danish Children: Associations between Pubarche, Adrenarche, Gonadarche and Body Composition. Eur J Endocrinol 2012, 168(2):129-36.
45. Hagen CP, Sørensen K, Anderson RA, Juul A. Serum levels of anti-Müllerian hormone in early maturing girls before, during and after suppression with GnRH agonist. Fertil Steril 2012, 98:1326-30.
5. Busch AS, Hagen CP, Assens M, Main KM, Almstrup K, Juul A. Differential Impact of Genetic Loci on Age at Thelarche and Menarche in Healthy Girls. J Clin Endocrinol Metab 2018; 103(1):228-234 6. Carlsson A, Sørensen K, Andersson A-M, Frederiksen H, Juul A. Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children. Endocr Connect 2018; 7(1):232-238
7. Greiber IK, Hagen CP, Busch AS, Mieritz MG, Aksglæde L, Main K, Almstrup K, Juul A. The AMH genotype (rs10407022 T>G) is associated with circulating AMH levels in boys, but not in girls. Endocr Connect 2018; 7(2):347-354
8. Mouritsen AK, Busch AS, Aksglaede L, Rajpert-De Meyts E, Juul A. Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys. Endocr Connect 2018; 7(3):460-465
9. Ridefelt P, Hilsted L, Juul A, Hellberg D, Rustad P. Pediatric reference intervals for general clinical chemistry components – merging of studies from Denmark and Sweden. Scand J Clin Lab Invest 2018; 78(5):365-372
10. Frederiksen H, Nielsen O, Skakkebaek NE, Juul A, Andersson A-M. UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents. Int J Hyg Environ Health 2017; 220(2):244-53
11. Johansen ML, Hagen CP, Mieritz MG, Wolthers OD, Heuck C, Petersen JH, Juul A. Pubertal Progression and Reproductive Hormones in Healthy Girls with Transient Thelarche. J Clin Endocrinol Metab 2017; 102(3):1001-1008
12. Søeborg T, Frederiksen H, Johannsen TH, Andersson A-M, Juul A. Isotope-dilution TurboFlow-LCMS/MS method for simultaneous quantification of ten steroid metabolites in serum. Clin Chim Acta 2017; 468:180-186
13. Busch AS, Hagen CP, Assens M, Main KM, Almstrup K, Juul A. Differential impact of genetic loci on age at thelarche and menarche in healthy girls. J Clin Endocrinol Metab 2018, 103(1):228-234
14. Kolby N, Busch A, Aksglaede L, Sørensen K, Petersen JH, Andersson AM, Juul A. Nocturnal Urinary Excretion of FSH and LH in Children and Adolescents with Normal and Early Puberty. J Clin Endocrinol Metab 2017, 102(10):3830-3838
15. Busch AS, Hagen CP, Main KM, Pereira A, Corvalan C, Almstrup K, Mericq V, Juul A. Genetic variation of Follicle-stimulating hormone action is associated with age at testicular growth in boys. J Clin Endocrinol Metab 2017, 102(5):1740-174916. Lindhardt Johansen M, Hagen CP, Mieritz MG, Wolthers OD, Heuck C, Petersen JH, Juul A. Pubertal Progression and Reproductive Hormones in Healthy Girls with Transient Thelarche. J Clin Endocrinol Metab 2016, 102(3):1001-1008.
17. Frederiksen H, Nielsen O, Skakkebaek NE, Juul A, Andersson AM. UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents. Int J Hyg Envir Health 2016, 220(2Pt A):244-253.
18. Almstrup K, Lindhardt Johansen M, Busch AS, Hagen CP, Nielsen JE, Petersen JH, Juul A. Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood. Sci Rep 2016, 6:28657.
19. Busch AS, Hagen CP, Almstrup K, Juul A. Circulating MKRN3 levels decline during puberty in healthy boys. J Clin Endocrinol Metab 2016, 101(6):2588-93.
20. Busch AS, Hagen CP, Almstrup K, Main KM, Juul A. Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls. Hum Reprod 2016, 31(4):897-904.
21. Mouritsen A, Søeborg T, Hagen CP, Mieritz MG, Johannsen TH, Frederiksen H, Andersson AM, Juul A. Longitudinal changes in serum concentrations of adrenal androgen metabolites and their ratios by LC-MS/MS in healthy boys and girls. Clin Chim Acta. 2015, 450:370-5.
22. Mieritz MG, Rakêt LL, Hagen CP, Nielsen JE, Talman L-LM, Petersen JH, Sommer SH, Main KM, Jørgensen N, Juul A. A Longitudinal Study of Growth, Sex Steroids and Insulin-like Growth Factor I in boys with Physiological Gynaecomastia. J Clin Endocrinol Metab 2015, 100 (10): 3752-9.
23. Känsäkoski J, Raivio T, Juul A, Tommiska J. A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early puberty. Pediatr Res 2015, 78 (6): 709-11.
24. Sørensen K, Juul A. Body Mass Index Percentile-for-Age Overestimates Adiposity in Early Compared with Late Maturing Pubertal Children. Eur J Endocrinol 2015, 173 (2): 227-35.
25. Hagen CP, S Rensen K, Mieritz MG, Johannsen TH, Almstrup K, Juul A. Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls. J Clin Endocrinol Metab 2015, 100(5): 1920-6.
26. Lawaetz J, Hagen CP, Mieritz MG, Jensen MB, Petersen JH, Juul A. Evaluation of 451 Danish boys with delayed puberty: Diagnostic use of a new puberty nomogram and effects of oral testosterone therapy. J Clin Endocrinol Metab 2015, 100(4): 1376-85
27. Hagen CP, Mieritz MG, Nielsen JE, Anand-Ivell R, Ivell R, Juul A. Longitudinal assessment of circulating INSL3 levels in healthy peripubertal girls. Fertil Steril 2015, 103(3):780-786.
28. Hagen CP, Sørensen K, Aksglæde L, Mouritsen A, Mieritz MG, Tinggaard J, Wohlfart-Veje C, Petersen JH, Main KM , Rajpert-DeMeyts E, Almstrup K, Juul A. Pubertal Onset in healthy girls is strongly influenced by genetic variation affecting FSH action. Scientific Reports 2014, 4:6412.
29. Søeborg T, Frederiksen H, Mouritsen A, Johannsen TH, Main KM, Jørgensen N, Petersen JH, Andersson AM, Juul A. The Influence of Age, Gender, Pubertal Stage, and Oral Contraceptives on Serum Levels of DHEA, DHEAS, 17α-Hydroxyprogesterone, Δ4-Androstenedione, Testosterone, and their Ratios Determined by TurboFlow-LC-MS/MS in 1798 Healthy Children, Adolescents, and Young Adults. Clinica Chimica Acta 2014, 437:6-13.
30. Bisgaard A, Sorensen K, Johannesen TH, Helge JW, Andersson AM, Juul A. Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and
adolescents. Int J Pediatr Endocrinol 2014, 1:7.
31. Mieritz MG, Sorensen K, Aksglaede L, Mouritsen A, Hagen CP, Hilsted L, Andersson AM,Juul A. Elevated serum levels of Free Triiodothyronine in Adolescent Boys with Gynaecomastia Compared to Controls. Eur J Endocrinol 2014, 171(2):193-8.
32. Mouritsen A, Søeborg T, Holm Johannsen T, Aksglaede L, Sørensen K, Hagen CP, Mieritz MG, Frederiksen H, Andersson AM, Juul A. Longitudinal changes in circulating testosterone levels
determined by LC-MS/MS and by a commercially available radioimmunoassay in healthy girls and boys during the pubertal transition. Horm Res Paediatr 2014, 82(1):12-7.
33. Lindhardt Johansen M, Anand-Ivell R, Mouritsen A, Hagen CP, Mieritz MG, Søeborg T, Johannsen TH, Main KM, Andersson AM, Ivell R, Juul A. Serum levels of Insulin-like factor 3, Anti-Müllerian Hormone, Inhibin B and Testosterone during pubertal transition in healthy boys: A longitudinal pilot study. Reproduction 2014, 147(4):529-35.
34. Tinggaard J, Aksglæde L, Sørensen K, Mouritsen A, Wohlfahrt Veje C, Hagen C, Mieritz MG, Jørgensen N, Wolthers OD, Heuck C, Petersen JH, Main KM, Juul A. The 2014 Danish references from birth to 20 years for height, weight and body mass index. Acta Paed Scand 2014, 103(2):214-24.
35. Mieritz MG, Sørensen K, Aksglæde L, Mouritsen A, Hagen CP, Hilsted L, Andersson AM, Juul A. Elevated serum IGF-I, but unaltered sex steroid levels, in healthy boys with pubertal gynaecomastia. Clin Endocrinol 2013, 80(5):691-8.
36. Munch-Andersen T, Sorensen K, Aachmann-Andersen NJ, Aksglaede L, Juul A, Helge JW. Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. Int
J Circumpolar Health 2013, 7;72.
37. Mouritsen AM, Frederisken H, Sørensen K, Aksglæde L, Hagen C, Skakkebæk NE, Main KM, Andersson AM, Juul A. Urinary Phthalates from 168 Girls and Boys measured twice a year during a 5 Year Period: Associations with Adrenal Androgen Levels and Puberty. J Clin Endocrinol Metab 2013, 98(9): 3755-64.
38. Hagen CP, Aksglaede L, Sørensen K; Mouritsen A,; Mieritz MG, Main KM, Petersen JH, Almstrup K, Rajpert-De Meyts E, Anderson RA, Juul A. FSHB –211 and FSHR 2039 polymorphisms affect serum levels of FSH and AMH in healthy girls: a longitudinal cohort study. Fertil Steril 2013, 100(4):1089-95.
39. Nielsen J, Jensen RB, Juul A. Increased Sex Hormone-Binding Globulin Levels in Children and Adolescents with thyrotoxicosis. Horm Res Pediatr 2013, 79: 157-61.
40. Søeborg T, Frederiksen H, Fruekilde P, Johannsen TH, Juul A, Andersson AM. Serum concentrations of DHEA, DHEAS, 17α-hydroxyprogesterone, ∆4-androstenedione and testosterone in children determined by TurboFlow-LC-MS/MS Clinica Chimica Acta 2013, 419: 95-101.
41. Frederiksen H, Aksglæde L, Sørensen K, Nielsen O, Main KM, Skakkebæk NE, Juul A, Andersson AM. Bisphenol A and other phenols in urine from Danish children and adolescents analyzed by isotope diluted TurboFlow-LC-MS/MS. Int J Hygiene Envir Health 2013, S1438-4639(13)00016-3.
42. Mouritsen A, Hagen CP, Sørensen K, Aksglæde L, Mieritz MG, Main KM, Almstrup K, Rajpert-DeMeyts E, Juul A. Androgen Receptor CAG Repeat length is Associated with Body Fat and Serum SHBG in Boys: A prospective Cohort Study. J Clin Endocrinol Metab 2013, 98(9): 3755-64.
43. Munch-Andersen T, Sorensen K, Andersen LB, Aachmann-Andersen NJ, Aksglaede L, Juul A, Helge JW. Adverse metabolic risk profiles in Greenlandic Inuit children compared to Danish Children. Obesity 2013, 21(6): 1226-31.
44. Mouritsen A, Aksglæde L, Sørensen K, Hagen CP, Petersen JH, Main KM, Juul A. The Pubertal Transition in 179 Healthy Danish Children: Associations between Pubarche, Adrenarche, Gonadarche and Body Composition. Eur J Endocrinol 2012, 168(2):129-36.
45. Hagen CP, Sørensen K, Anderson RA, Juul A. Serum levels of anti-Müllerian hormone in early maturing girls before, during and after suppression with GnRH agonist. Fertil Steril 2012, 98:1326-30.
46. Hilsted L, Rustad P, Aksglæde L, Sørensen, Juul A. Recommended Nordic paediatric reference intervals for 21 common biochemical properties. Scand J Clin Lab Invest 2013; 73(1):1-9.
47. Nielsen LB, Wang C, Sørensen K, Bang-Bertelsen CH, Hansen L, Andersen ML, Hougaard P, Juul A, Zhang CY, Pociot F, Mortensen HB. Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls – evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp Diabetes Res 2012; in press.
48. Mieritz MG, Frederiksen H, Sorensen K, Aksglaede L, Mouritsen A, Hagen CP, Skakkebaek NE, Andersson AM, Juul A. Urinary phthalate excretion in 555 healthy Danish Boys with and without pubertal gynaecomastia. Int J Androl 2012; 35: 227-235.
49. Sørensen K, Aksglæde L, Petersen JH, Andersson AM, Juul A. Serum IGF-I and Insulin levels in girls with normal and precocious Puberty. Eur J Endocrinol 2012, 166: 903-910.
50. Frederiksen H, Sorensen K, Mouritsen A, Aksglaede L, Hagen CP, Petersen JH, Skakkebaek NE, Andersson AM, Juul A. High urinary phthalate concentration associated with delayed pubarche in girls. Int J Androl 2012; 35: 216-226.
51. Hagen CP, Aksglaede L, Sørensen K, Mouritsen A, Andersson AM, Petersen JH, Main KM, Juul A. Individual serum levels of circulating Anti-Müllerian Hormone in healthy girls persist through childhood and adolescence: a longitudinal cohort study. Human Reproduction 2012; 27(3):861-6.
52. Tommiska J, Sørensen K, Aksglaede L, Koivu R, Puhakka L, Juul A, Raivio T. LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty. BMC Research Notes 2011, 4:363.
53. Frederiksen H, Aksglaede L, Sorensen K, Skakkebaek NE, Juul A, Andersson AM. Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake. Envir Res 2011, 111(5):656-63.
54. Aksglaede L, Sørensen K, Boas M, Mouritsen A, Hagen C, Jensen RB, Petersen JH, Linneberg A, Andersson A-M, Main KM, Skakkebæk NE and Juul A. Changes in Anti-Müllerian Hormone (AMH) throughout the lifespan: A population based study of 1027 healthy males from birth (cord blood) to the age of 69 years. J Clin Endocrinol Metab 2010, 95(12):5357-64.
55. Hagen CP, Aksglaede L, Sørensen K, Main KM, Boas M, Cleemann L, Holm K, Gravholt CH, Andersson AM, Pedersen AT, Petersen JH, Linneberg A, Kjaergaard S, Juul A. Serum levels of Anti-Müllerian Hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. J Clin Endocrinol Metab 2010, 95(11):5003-10.
56. Sørensen K, Mouritsen A, Mogensen SS, Aksglaede L, Juul A. Insulin Sensitivity and Lipid profiles in Girls with Central Precocious Puberty Before and During Gonadal Suppression. J Clin Endocrinol Metab 2010, 25(8): 3736-44.
57. Sørensen K, Aksglaede L, Petersen JH, Leffers H, Juul A. The Growth Hormone Receptor Gene Exon 3 Deletion is associated with small birth size and early pubertal onset in healthy boys. J Clin Endocrinol Metab 2010; 95(6): 2819-26.
58. Sørensen K, Aksglæde L, Petersen JH, Juul A. Recent changes in pubertal timing in healthy Danish boys: Association with body mass index. J Clin Endocrinol metab 2010 Jan; 95(1):263-70.
59. Courant F, Aksglaede L, Antignac JP, Monteau F, Sørensen K, Andersson AM, Skakkebæk NE, Juul A, Le Bisec B. Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method. J Clin Endocrinol metab 2010; 95(1): 82-92.Hormone Receptor Exon 3 Deletion Gene Polymorphism on Glucose Metabolism, Lipids and IGF-I levels during puberty. J Clin Endocrinol metab 2009, Aug; 94(8):2966-9.
61. Bjørnhart B, Juul A, Nielsen S, Zak M, Svenningensen P, Müller K. Cartilage Oligomeric Matrix Protein (COMP) in patients with juvenile idiopathic arthritis: relation to growth and disease activity. J Rheumatol 2009, 36: 1749-54.
62. Aksglaede L, Sorensen K, Petersen JH, Skakkebæk NE, Juul A. Recent decline in age at breast development. The COPENHAGEN Puberty Study. Pediatrics 2009, 123(5):e932-9.
63. Sørensen K, Aachmann-Andersen NJ, Petersen JH, Hilsted L, Helge JW, Juul A. Sex Hormone-Binding Globulin Levels Predict Insulin Sensitivity, Disposition Index and Cardiovascular Risk During Puberty. Diabetes Care 2009, May;32(5):909-14 .
64. Juul A, Sørensen K, Aksglaede L, Garn I, Rajpert-De Meyts E, Hullstein I, Hemmersbach P, Ottesen AM. A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys. J Clin Endocrinol metab 2009, 94: 1005-1011.
47. Nielsen LB, Wang C, Sørensen K, Bang-Bertelsen CH, Hansen L, Andersen ML, Hougaard P, Juul A, Zhang CY, Pociot F, Mortensen HB. Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls – evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp Diabetes Res 2012; in press.
48. Mieritz MG, Frederiksen H, Sorensen K, Aksglaede L, Mouritsen A, Hagen CP, Skakkebaek NE, Andersson AM, Juul A. Urinary phthalate excretion in 555 healthy Danish Boys with and without pubertal gynaecomastia. Int J Androl 2012; 35: 227-235.
49. Sørensen K, Aksglæde L, Petersen JH, Andersson AM, Juul A. Serum IGF-I and Insulin levels in girls with normal and precocious Puberty. Eur J Endocrinol 2012, 166: 903-910.
50. Frederiksen H, Sorensen K, Mouritsen A, Aksglaede L, Hagen CP, Petersen JH, Skakkebaek NE, Andersson AM, Juul A. High urinary phthalate concentration associated with delayed pubarche in girls. Int J Androl 2012; 35: 216-226.
51. Hagen CP, Aksglaede L, Sørensen K, Mouritsen A, Andersson AM, Petersen JH, Main KM, Juul A. Individual serum levels of circulating Anti-Müllerian Hormone in healthy girls persist through childhood and adolescence: a longitudinal cohort study. Human Reproduction 2012; 27(3):861-6.
52. Tommiska J, Sørensen K, Aksglaede L, Koivu R, Puhakka L, Juul A, Raivio T. LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty. BMC Research Notes 2011, 4:363.
53. Frederiksen H, Aksglaede L, Sorensen K, Skakkebaek NE, Juul A, Andersson AM. Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake. Envir Res 2011, 111(5):656-63.
54. Aksglaede L, Sørensen K, Boas M, Mouritsen A, Hagen C, Jensen RB, Petersen JH, Linneberg A, Andersson A-M, Main KM, Skakkebæk NE and Juul A. Changes in Anti-Müllerian Hormone (AMH) throughout the lifespan: A population based study of 1027 healthy males from birth (cord blood) to the age of 69 years. J Clin Endocrinol Metab 2010, 95(12):5357-64.
55. Hagen CP, Aksglaede L, Sørensen K, Main KM, Boas M, Cleemann L, Holm K, Gravholt CH, Andersson AM, Pedersen AT, Petersen JH, Linneberg A, Kjaergaard S, Juul A. Serum levels of Anti-Müllerian Hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. J Clin Endocrinol Metab 2010, 95(11):5003-10.
56. Sørensen K, Mouritsen A, Mogensen SS, Aksglaede L, Juul A. Insulin Sensitivity and Lipid profiles in Girls with Central Precocious Puberty Before and During Gonadal Suppression. J Clin Endocrinol Metab 2010, 25(8): 3736-44.
57. Sørensen K, Aksglaede L, Petersen JH, Leffers H, Juul A. The Growth Hormone Receptor Gene Exon 3 Deletion is associated with small birth size and early pubertal onset in healthy boys. J Clin Endocrinol Metab 2010; 95(6): 2819-26.
58. Sørensen K, Aksglæde L, Petersen JH, Juul A. Recent changes in pubertal timing in healthy Danish boys: Association with body mass index. J Clin Endocrinol metab 2010 Jan; 95(1):263-70.
59. Courant F, Aksglaede L, Antignac JP, Monteau F, Sørensen K, Andersson AM, Skakkebæk NE, Juul A, Le Bisec B. Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method. J Clin Endocrinol metab 2010; 95(1): 82-92.Hormone Receptor Exon 3 Deletion Gene Polymorphism on Glucose Metabolism, Lipids and IGF-I levels during puberty. J Clin Endocrinol metab 2009, Aug; 94(8):2966-9.
61. Bjørnhart B, Juul A, Nielsen S, Zak M, Svenningensen P, Müller K. Cartilage Oligomeric Matrix Protein (COMP) in patients with juvenile idiopathic arthritis: relation to growth and disease activity. J Rheumatol 2009, 36: 1749-54.
62. Aksglaede L, Sorensen K, Petersen JH, Skakkebæk NE, Juul A. Recent decline in age at breast development. The COPENHAGEN Puberty Study. Pediatrics 2009, 123(5):e932-9.
63. Sørensen K, Aachmann-Andersen NJ, Petersen JH, Hilsted L, Helge JW, Juul A. Sex Hormone-Binding Globulin Levels Predict Insulin Sensitivity, Disposition Index and Cardiovascular Risk During Puberty. Diabetes Care 2009, May;32(5):909-14 .
64. Juul A, Sørensen K, Aksglaede L, Garn I, Rajpert-De Meyts E, Hullstein I, Hemmersbach P, Ottesen AM. A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys. J Clin Endocrinol metab 2009, 94: 1005-1011.
The COPENHAGEN Puberty Study I (1991 – 1992)
65. Agate L, Mariotti S, Elisei R, Mossa P, Pacini F, Molinaro E, Grasso L, Masserini L, Mokhort T, Vorontsova T, Tronko MD, Tsyb A, Feldt-Rasmussen U, Juul A, Pinchera A. Thyroid autoantibodies and thyroid function in subjects exposed to Chernobyl fallout during childhood: evidence for a transient radiation-6 induced elevation of serum ATA without an increase in thyroid autoimmune disease. J Clin Endocrinol Metab 2008, 93(7):2729-36.66. Sorensen K, Andersson AM, Skakkebaek NE, Juul A. Serum sex hormone binding globulin in healthy children and in girls with precocious puberty before and during GnRH agonist treatment. J Clin Endocrinol Metab. 2007, 92(8):3189-96.
67. Juul A, Teilmann G, Scheike TS, Hertel NT, Holm K, Laursen EM, Main KM, Skakkebæk NE. Pubertal development in Danish children: comparison of recent European and US data. Int J Androl 2006; 29:247-55.
68. Sehested A, Juul A, Andersson AM, Petersen JH, Müller J, Skakkebæk NE. Serum inhibin A and inhibin B in healthy prepubertal, pubertal and adolescent girls and adults women: relation to age, stage of puberty, menstrual cycle, FSH, LH and estradiol levels. J Clin Endocrinol Metab 2000, 85: 1634-1640.
69. Juul A, Fisker S, Scheike T, Hertel T, Müller J, Ørskov H, Skakkebæk NE. Serum levels of growth hormone binding protein in children with normal and precocious puberty: Relation to age, gender, body composition, and gonadal steroids. Clin Endocrinol 2000; 52: 165-172.
70. Yu H, Nicar MJ, Khoshravi MJ, Diamandais,A, van Doorn J, Juul A. Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6 and ALS) in blood circulation. J Clin Lab Anal 1999; 13(4): 166-72.
71. Juul A, Møller S, Mosfeldt-Laursen E, Rasmussen MH, Scheike T, Pedersen SA, Kastrup KW, Yu H, Mistry J, Rasmussen S, Müller J, Henriksen J, Skakkebæk NE. The acid-labile subunit of human ternary insulin-like growth factor binding protein complex in serum: Hepatosplancnic release, diurnal variation, circulating concentrations in healthy subjects, and diagnostic use in patients with growth hormone deficiency. J Clin Endocrinol Metab 1998; 83(12): 4408-4415.
72. Lund AM, Hansen M, Kollerup G, Juul A, Teisner B, Skovby F. Collagen-derived markers of bone metabolism in osteogenesis imperfecta. Acta Paediatr 1998; 87: 1131-1137.
73. Kiess W, Anil M. Blum WF, Englaro P, Juul A, Attanasio A, Dötsch J, Rascher W. Leptin serum levels in children and adolescents with insulin-dependent diabetes mellitus in relation to metabolic control and body mass index. Eur J Endocrinol, 1998; 138: 501-509.
74. Andersson AM, Juul A, Petersen JH, Müller J, Groome NP, Skakkebæk NE. Serum inhibin B in healthy pubertal and adolescent boys: Relation to age, stage of Puberty, and folliclestimulating hormone, luteinizing hormone, testosterone and estradiol levels. J Clin Endocrinol Metab 1997; 82: 3976-3981.
75. Blum WF, Englaro P, Hanitsch S, Juul A, Hertel NT, Müller J, Skakkebæk NE, Heiman M, Birkett M, Attanasio AM, Kiess W, Rascher W. Plasma Leptin levels in healthy children and adolescents:
Dependence on body mass index, body fat mass, gender, pubertal stage and testosterone. J Clin Endocrinol Metab 1997; 82: 2904-2910.
76. Juul A, Holm K, Kastrup KW, Pedersen SA, Michaelsen KF, Scheike T, Rasmussen S, Müller J, Skakkebæk NE. Free Insulin-like Growth Factor (IGF)-I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of GH deficiency. J Clin Endocrinol Metab 1997; 82: 2497-2502.
77. Demir A, Voutilainen R, Juul A, Dunkel L, Alfthan H, Skakkebæk NE, Stenman U-H. Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty. J Clin Endocrinol Metab 1996, 81:2963-2967.
78. Juul A, Flyvbjerg A, Frystyk J, Müller J, Skakkebæk NE. Serum concentrations of free and total insulin-like growth factor (IGF)-I, IGF binding proteins (IGFBP-1 and -3) and IGFBP-3 protease activity in boys with normal and precocious puberty. Clin Endocrinol 1996, 44: 515-523.
79. Hertel NT, Scheike T, Juul A, Main K, Holm K, Bach Mortensen N, Skakkebæk NE, Müller J. Body Proportions in Danish Children. Ugeskr f Læger 1995, 157: 6876-6881.
80. Juul A, Dalgaard P, Blum WF, Bang P, Hall K, Michaelsen KF, Müller J, Skakkebæk NE. Serum levels of Insulin-like Growth Factor (IGF) Binding Protein-3 in healthy infants, children and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index and pubertal maturation. J Clin Endocrinol Metab 1995, 80: 2534-2542.
81. Main K, Jarden M, Angelo L, Dinesen B, Hertel NT, Juul A, Müller J, Skakkebæk NE. The impact of Gender and Puberty on Reference Values for Urinary Growth Hormone Excretion: A Study of 3 Morning Urine Samples in 517 Healthy Children and Adults. J Clin Endocrinol Metab 1994, 79: 865-871.
82. Juul A, Bang P, Hertel NT, Main K, Dalgaard P, Jørgensen K, Müller J, Hall K, Skakkebæk NE. Serum Insulin-like growth factor-I (IGF-I) in 1030 healthy children, adolescents and adults; relation to age, sex, stage of puberty, testicular size and body mass index. J Clin Endocrinol Metab 1994, 78: 744-752.
83. Blum WF, Horn N, Kratzsch J, Jørgensen JOL, Juul A, Teale D, Mohnike K, Ranke MB. Clinical studies of IGFBP-2 by radioimmunoassay. Growth Regulation 1993; 3: 100-104.
84. Hertel NT, Stoltenberg M, Juul A, Main K, Müller J, Nielsen CT, Lorenzen I, Skakkebæk NE. Serum concentrations of Type I and III procollagen propeptides in Healthy Children and Girls with Central Precocious Puberty during treatment with Gonadotropin-releasing Hormone Analog and Cyproterone Acetate. J Clin Endocrinol Metab 1993; 76: 924-7.